In the Journal of AAPOS, researchers described the first case report of the use of oral fluorescein and Optos noncontact ultra-widefield (UWF™) fundus and angiographic imaging in an office setting on a non-sedated infant with incontinentia pigmenti. The UWF imaging system also correctly identified retinal neovascularization and avascular retinal zones, which subsequently permitted targeted laser treatment of retinal capillary nonperfused areas. This approach is less invasive for pediatric patients, obviates the potential risks associated with IV fluorescein and enables the review of both healthy and diseased retinal vasculature in a single image.

Patel CK, Fung THM, Muqit MMK, Mordant DJ, Geh V. Non-contact ultra-widefield retinal imaging and fundus fluorescein angiography of an infant with incontinentia pigmenti without sedation in an ophthalmic office setting. Journal of AAPOS. 2013.

Optos UWF™ image of the right eye of a 41 week old infant who had persistent threshold disease (stage 3 zone 2 ROP with plus disease) despite previous laser therapy.